Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
Specificity and Use
FPR2 / FPRL1 antibody was raised against a short peptide corresponding to aa181-192 (ASWGGTPEERLK) on FPRL-1 (KLH). Percent identity by BLAST analysis: Human, Chimpanzee (100%); Gorilla, Monkey (92%); Orangutan (83%).
Recognizes human FPRL1.
Suitable for use in ELISA. Myeloma. Sp2/0-Ag14.
Lyophilized from 0.01 M PBS, pH 7.0
Sterile 40-50% glycerol, distilled water.
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstituted product is stable for 12 months at -20°C Aliquot and store at -20°C.
FPRL1, a Chemoattractant Receptor also called Lipoxin A4 Receptor, functions as a component of the inflammatory response. Its stimulation results in neutrophil activation and desensitization of chemokine receptors in monocytes (Le et al., 2000). The receptor is up-regulated by interleukin-1 in normal human synovial fibroblasts.