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Anti-FOXO1 / FKHR Antibody (phospho-Ser256) LS-C15214

Catalog Size Price
LS-C15214-100 100 µl Unavailable

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100% Guaranteed
Rabbit Polyclonal (IgG) to Human FOXO1 / FKHR
Human, Mouse, Rat
Western blot
Unconjugated

Details

Human FOXO1 / FKHR
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Protein A purified
Unmodified

Applications

Western blot (1:1000)

Specificity and Use

FOXO1 / FKHR antibody was raised against synthetic phosphopeptide (KLH coupled) corresponding to residues around Ser256 of human FKHR.
pSer256
Detects endogenous levels of total levels of FKHR only when phosphorylated at Ser256. Cross-reacts with phosphorylated AFX. Species cross-reactivity: Human, mouse, rat.
Suitable for use in Western Blot. Western Blot: 1:1000. Incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween 20 at 4?C with gentle shaking overnight.

Packaging

10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/ml BSA, 50% glycerol. No preservative added.
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
For research use only.

About FOXO1 / FKHR

Q12778 NM_002015 NP_002006.2

FOXO1 Antibody, FKHR Antibody, Forkhead in rhabdomyosarcoma Antibody, FOXO1A Antibody, FKH1 Antibody, Forkhead box protein O1 Antibody, Forkhead box protein O1A Antibody, Forkhead box O1 Antibody, Forkhead box o1a Antibody, Forkhead domain protein fkhr Antibody

Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass.

Requested From: 
Date Requested: 10/22/2017

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