Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Monkey, Chicken (tested or 100% immunogen sequence identity)
Mouse (at least 90% immunogen sequence identity)
IHC - Paraffin
Specificity and Use
FOXC1 antibody was raised against synthetic peptide C-DAVKDKEEKDRLH from an internal region of human FOXC1 (NP_001444.2). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Elephant, Opossum, Chicken (100%); Mouse (92%).
FOXC1 Antibody, Forkhead-like 7 Antibody, FREAC3 Antibody, FKHL7 Antibody, Forkhead-related activator 3 Antibody, Forkhead-related protein FKHL7 Antibody, IGDA Antibody, IHG1 Antibody, IRID1 Antibody, Forkhead box protein C1 Antibody, Mesenchyme fork head protein 1 Antibody, Myeloid factor-delta Antibody, ARA Antibody, Forkhead box C1 Antibody, FREAC-3 Antibody, RIEG3 Antibody
Forkhead box C1 (FOXC1) belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of FOXC1 has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in FOXC1 cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.