Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [107.1A4]
IHC - Paraffin (1:100 - 1:1000)
IHC - Frozen (1:100 - 1:1000)
Specificity and Use
FOLH1 / PSMA antibody was raised against prostate cancer cell line LNCaP
recognizes a distinct conformational and unique epitope in the extracellular domain of PSMA.PSMA is a type II membrane glycoprotein of 100kDa that has a short intracellular N-terminaldomain (residues 1 to 18), a transmembrane region (residues 19 to 43) and a large extracellulardomain consisting of residues 44 to 750.
PBS with 0.09% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
FOLH1 / PSMA is a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney.