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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FHIT Antibody (C‑Terminus) LS‑C193971
Antibody
FHIT antibody LS-C193971 is an unconjugated rabbit polyclonal antibody to human FHIT. Validated for IHC and WB.
Catalog
Size
Price
LS-C193971-100
100 µg
Unavailable

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Product Description

FHIT antibody LS-C193971 is an unconjugated rabbit polyclonal antibody to human FHIT. Validated for IHC and WB.
About FHIT
Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival, such as CCND1 and BIRC5. Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways. P49789 NM_002012 NP_002003.1

FHIT Antibody, AP3Aase Antibody, Dinucleosidetriphosphatase Antibody, Fragile histidine triad Antibody, Fragile histidine triad gene Antibody, AP3A hydrolase Antibody, Bis(5-adenosyl)-triphosphatase Antibody, FRA3B Antibody, Tumor suppressor protein Antibody


Specifications

Target
Human FHIT
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC (25 µg/ml)
  • Western blot (5 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
FHIT antibody was raised against a synthetic peptide corresponding to the C terminal part of human FHIT.
Epitope
C-Terminus
Specificity
Human FHIT
Presentation
Lyophilized from PBS, pH 7.4, 1% BSA, 0.05% sodium azide
Reconstitution
1 ml Distilled water
Storage
Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/20/2018

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