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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FGFR1 / FGF Receptor 1 Antibody (N‑Terminus, clone M2F12) IHC‑plus™ LS‑B6232
Note: This antibody replaces LS-C83405
FGF Receptor 1 antibody LS-B6232 is an unconjugated mouse monoclonal antibody to FGF Receptor 1 (FGFR1) from human, mouse and rat. Validated for IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B6232-50
50 µg (1 mg/ml)
Unavailable

Popular FGFR1 / FGF Receptor 1 Products

Antibody
Species: Bovine, Human, Mouse, Rat, Guinea pig, Chicken
Applications: IHC, IHC - Frozen, Western blot, Immunoprecipitation, ELISA
Antibody
Species: Human
Applications: Western blot, Immunoprecipitation, Flow Cytometry
Anti-FGFR1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3031 concentration 4 ug/ml.
Species: Human, Monkey, Bat, Bovine, Dog, Horse
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
IHC of paraffin-embedded human breast carcinoma tissue, using FGFR1 (Ab-766) Antibody. The picture on the right is treated with the synthesized peptide.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Anti-FGFR1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6250 concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation

Product Description

FGF Receptor 1 antibody LS-B6232 is an unconjugated mouse monoclonal antibody to FGF Receptor 1 (FGFR1) from human, mouse and rat. Validated for IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
About FGFR1 / FGF Receptor 1
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. P11362 NM_023110 CAA47375.1

FGFR1 Antibody, BFGF receptor Antibody, BFGF-R Antibody, BFGF-R-1 Antibody, CD331 Antibody, Cek1 Antibody, CD331 antigen Antibody, FGFR1/PLAG1 fusion Antibody, FLT2 Antibody, Fgf-flg Antibody, FGFBR Antibody, FGFR-1 Antibody, Fms-like tyrosine kinase 2 Antibody, HBGFR Antibody, HH2 Antibody, Hydroxyaryl-protein kinase Antibody, FGF receptor 1 Antibody, Fms-related tyrosine kinase 2 Antibody, Proto-oncogene c-Fgr Antibody, BFGFR Antibody, CEK Antibody, FLT-2 Antibody, HBGF receptor Antibody, KAL2 Antibody, OGD Antibody


Specifications

Target
Human FGFR1 / FGF Receptor 1
Host
Mouse
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal [M2F12]
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • IHC - Frozen
  • Western blot (1 µg/ml)
  • Immunoprecipitation
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Recombinant human ectodomain of FGFr1a expressed in E. coli beginning with pro23; antigen contained NH2-terminal gly-ser-pro-gly-ile and C-terminal glu-phe sequences.
Epitope
N-Terminus
Specificity
Reacts with the NH2-terminus of unique NH2-terminal Ig loop of FGFr1. Epitope is within the sequence between glu30 and ala74 of FGFr1a. Reacts with human, rat, and mouse receptor. Other species untested.
Usage
Western blotting: at 1 ug/ml recognizes 10 ng recombinant bacterial, baculo-viral, or native FGFr1. Immunoprecipitation: native, nuclear, recombinant, and ligand-labeled FGFr1. Immunohistochemistry: frozen sections of human glioblastomas, paraformaldehyde fixed cells and nuclei, human myocardial biopsies, FFPE human tissues.
Presentation
PBS, pH 7.4
Storage
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Anti-FGFR1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6232 concentration 10 ug/ml.
Anti-FGFR1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6232 concentration 10 ug/ml.

Immunohistochemistry

Anti-FGFR1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6232 concentration 10 ug/ml.
Anti-FGFR1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6232 concentration 10 ug/ml.

Immunohistochemistry

Anti-FGFR1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6232 concentration 10 ug/ml.
Anti-FGFR1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6232 concentration 10 ug/ml.

Immunohistochemistry

Anti-FGFR1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6232 concentration 10 ug/ml.
Anti-FGFR1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6232 concentration 10 ug/ml.


Requested From: 
Date Requested: 6/19/2018

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