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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FCAR / CD89 Antibody LS‑C14005
CD89 antibody LS-C14005 is an unconjugated mouse monoclonal antibody to human CD89 (FCAR). Validated for ELISA, Flow, IP and WB.
Antibody
Catalog
Size
Price
LS-C14005-200
200 µg
$590

Popular FCAR / CD89 Products

Antibody
Species: Human
Applications: Western blot
Antibody
Species: Human
Applications: Western blot, ELISA
Flow cytometry of human peripheral blood granulocytes with Mouse anti-Human CD89:Low endotoxin This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human
Applications: Western blot, Immunoprecipitation, Flow Cytometry, ELISA, Functional Assay
Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: Western blot, Immunoprecipitation, Flow Cytometry, ELISA

Product Description

CD89 antibody LS-C14005 is an unconjugated mouse monoclonal antibody to human CD89 (FCAR). Validated for ELISA, Flow, IP and WB.

Specifications

Target
Human FCAR / CD89
Synonyms
FCAR, CD89 antigen, Fc alpha receptor, IgA Fc receptor, CD89
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated. Also available conjugated with AP, Biotin, FITC, HRP, PE.
Purification
Purified
Modifications
Unmodified
Applications
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry (1:50 - 1:100)
  • ELISA
  • (applications tested for the base form of this product only)
Immunogen
FCAR / CD89 antibody was raised against recombinant soluble human Fc alpha R.
Specificity
Recognizes the human CD89 cell surface antigen, a 50-75kD cell surface glycoprotein that is also known as the IgA receptor (Fc alpha R). CD89 is expressed by peripheral blood monocytes and neutrophils. 3H1742 blocks binding of IgA to the Fc alpha R and also inhibits neutrophil phagocytosis of IgA complexes. The preservative free format of this antibody is recommended for functional studies.
Usage
Flow Cytometry: 1:50-1:100. ELISA. Immunoprecipitation. Western Blot.
Presentation
PBS, pH 7.2, 0.1% Sodium Azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About FCAR / CD89
FCAR / CD89 is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. P24071 NM_002000 NP_001991.1


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Requested From: United States
Date Requested: 10/22/2018

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