Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 1C2] (IgG1,k) to Human F9 / Factor IX
Western blot, ELISA
Human F9 / Factor IX
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [1C2]
Protein A/G purified
Specificity and Use
F9 / Factor IX antibody was raised against factor IX isolated from human plasma.
Has specificity for native human factor IX. Epitope specificity differs from that of clone 6F98 as determined by inhibition ELISA. Reacts strongly with native factor IX. Strong reaction is seen in ELISA with native factor IX directly coated onto the microtiter well, and also when tested in sandwich ELISA in combination with a polyclonal antibody against factor IX. In Western blotting after SDS-PAGE reacts with factor IX in non-reduced form only.
Suitable for use in ELISA and Western Blot. ELISA: 1:6000.
PBS, pH 7.2, 15 mM sodium azide.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
F9 Antibody, Christmas Disease Antibody, Coagulation factor IX Antibody, Factor IX Deficiency Antibody, FIX Antibody, HEMB Antibody, F9 p22 Antibody, Factor 9 Antibody, Factor IX Antibody, Factor IX F9 Antibody, FIX F9 Antibody, Haemophilia B Antibody, THPH8 Antibody, Christmas factor Antibody, Hemophilia B Antibody, PTC Antibody, Serine protease Antibody
F9 / Factor IX is a vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII.