Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone M1] (IgG) to Human F13A1 / Factor XIIIa
Mouse Monoclonal [clone AC-1A1] (IgG1,k) to Human F13A1 / Factor XIIIa
Human F13A1 / Factor XIIIa
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [AC-1A1]
Specificity and Use
BALB/C mice were injected with recombinant human protein corresponding to A-subunit of coagulation Factor XIII.
Is specific to 160 kD protein known as Factor XIIIA. Factor XIII is a ß-globulin found in plasma and is composed of two subunits. Factor XIII-A is the catalytic subunit and is a dimmer of M.W. 160 kD. Factor XIII is a dermal dendrocyte marker and shows variable reaction with these types of tumors.
F13A1 / Factor XIIIa is the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin.