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Anti-ESRRA / ERR Alpha Antibody (Internal) IHC-plus™ LS-A5402

Ordering

Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $395
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100% Guaranteed 100% Guaranteed In Stock In Stock Publications Publications (3)
Rabbit Polyclonal to Human ESRRA / ERR Alpha
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig
IHC - Paraffin, Chromatin Immunoprecipitation
Unconjugated

Details

Human ESRRA / ERR Alpha
Rabbit
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig (tested or 100% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

IHC - Paraffin (8 - 24 µg/ml), Chromatin Immunoprecipitation

Specificity and Use

ESRRA / ERR Alpha antibody was raised against synthetic 15 amino acid peptide from internal region of human ESRRA. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Bat, Dog, Horse, Pig (100%); Gibbon (93%).
LS-E29065 - Liquid - 50 µg - $145.00
Internal
Human ESRRA. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

Publications (3)

1
Receptor interacting protein 140 regulates expression of uncoupling protein 1 in adipocytes through specific peroxisome proliferator activated receptor isoforms and estrogen-related receptor alpha. Debevec D, Christian M, Morganstein D, Seth A, Herzog B, Parker M, White R. Molecular endocrinology (Baltimore, Md.). 2007 21:1581-92. (ChrIP; Mouse) [Full Text Article] [PubMed:17456798] [PMC:PMC2072047]
2
Human fetal mesenchymal stem cells differentiate into brown and white adipocytes: a role for ERRalpha in human UCP1 expression. Morganstein DL, Wu P, Mane MR, Fisk NM, White R, Parker MG. Cell Research. 2010 20:434-44. (ChrIP; Human) [Full Text Article] [PubMed:20101261] [PMC:PMC2848839]
3
RIP140 expression is stimulated by estrogen-related receptor alpha during adipogenesis. Nichol D, Christian M, Steel JH, White R, Parker MG. The Journal of biological chemistry. 2006 Oct;281:32140-7. [Full Text Article] [PubMed:16923809]

About ESRRA / ERR Alpha

P11474 NM_004451 NP_004442.3

ESRRA Antibody, ERRa Antibody, ERR1 Antibody, HERR1 Antibody, NR3B1 Antibody, Steroid hormone receptor ERR1 Antibody, ERR-alpha Antibody, ERRalpha Antibody, ESRL1 Antibody, Estrogen receptor-like 1 Antibody

Estrogen-related receptor alpha (ERR alpha), a NR3 Steroid Receptor, was isolated based on sequence similarity in its DNA-binding domain to estrogen receptor alpha (ER alpha). ERR alpha has been shown to regulate the promoters of lactoferrin, medium-chain acyl CoA dehydrogenase, osteopontin, and thyroid receptor alpha, and it may affect cellular energy balance and bone formation.

Immunohistochemistry

Immunohistochemistry
Anti-ESRRA / ERR Alpha antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-ESRRA antibody LS-A5402 IHC of human breast carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Requested From: United States
Date Requested: 9/26/2016

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