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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ESR2 / ER Beta Antibody (aa468‑485) LS‑C15073
Antibody
ER Beta antibody LS-C15073 is an unconjugated rabbit polyclonal antibody to rat ER Beta (ESR2). Validated for WB.
Catalog
Size
Price
LS-C15073-200
200 µg
Unavailable

Popular ESR2 / ER Beta Products

Antibody
Species: Mouse
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot
Anti-ER-Beta antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B945 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat, Bat, Bovine, Pig, Rabbit
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human, Mouse, Rat
Applications: Western blot
Immunofluorescence of HeLa cells, using Estrogen Receptor-beta (Ab-105) Antibody. The picture on the right is treated with the synthesized peptide.
Species: Human, Mouse, Rat
Applications: Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Antibody
Species: Human, Mouse, Rat
Applications: IHC, Western blot

Product Description

ER Beta antibody LS-C15073 is an unconjugated rabbit polyclonal antibody to rat ER Beta (ESR2). Validated for WB.
About ESR2 / ER Beta
Estrogen receptor beta (ER beta), a NR3 Steroid Receptor, has been shown to have physiological functions in the central nervous system, cardiovascular system, immune system, urogenital tract, gastrointestinal tract, and in bone, kidney, and lung. Mice lacking the gene for ER beta show defective ovary development, reduced fertility, abnormal bladder and prostate development, and impaired vascular system functions that lead to hypertension in aging. Q92731 NM_001437 NP_001428.1

ESR2 Antibody, ESTRB Antibody, ER Beta Antibody, ERbeta Antibody, ER-BETA Antibody, ESR-BETA Antibody, ESRB Antibody, Estrogen receptor 2 (ER beta) Antibody, NR3A2 Antibody, Estrogen receptor beta Antibody, Estrogen receptor beta 4 Antibody


Specifications

Target
Rat ESR2 / ER Beta
Host
Rabbit
Reactivity
Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1 - 2 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
ESR2 / ER Beta antibody was raised against kLH-conjugated, synthetic peptide corresponding to amino acids 468-485 (SSTEDSKNKESSQNLQSQ) of rat estrogen receptor beta (ERb). The immunizing sequence has 16/17 identical amino acids in mouse and 14/18 in human. Percent identity by BLAST analysis: Rat (100%); Mouse, Guinea pig (83%).
Epitope
aa468-485
Specificity
Recognizes ERb, Mr ~53-65kD. Does not cross-react with ERb. Species cross-reactivity: Rat and human.
Usage
Suitable for use in Western Blot. Western Blot: 1-2 ug/ml detected ERb in MCF-7 RIPA lysates.
Presentation
0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide, 30% glycerol.
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/19/2018

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