Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
SETDB1 Antibody, H3-K9-HMTase4 Antibody, ESET Antibody, KMT1E Antibody, H3-K9-HMTase 4 Antibody, KG1T Antibody, SET domain, bifurcated 1 Antibody, SET domain bifurcated 1 Antibody, KIAA0067 Antibody, Lysine N-methyltransferase 1E Antibody
Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. H3 'Lys-9' trimethylation is coordinated with DNA methylation.
Western blot of SETDB1(arrow) using rabbit polyclonal SETDB1 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SETDB1 gene (Lane 2) (Origene Technologies).
Western blot of anti-SETDB1 Pabin Ramos cell line lysate (35 ug/lane). SETDB1(arrow) was detected using the purified antibody.
Requested From: United States
Date Requested: 12/8/2016