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Anti-ERBB4 / HER4 Antibody (C-Terminus) LS-C6703

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Wt. Vol. Conc. Price
200 µg - 1 mg/ml $515
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
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Rabbit Polyclonal (IgG) to Human ERBB4 / HER4
Human, Mouse, Rat
Western blot, Immunoprecipitation
Unconjugated

Details

Human ERBB4 / HER4
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Protein A purified

Applications

Western blot, Immunoprecipitation

Specificity and Use

ERBB4 / HER4 antibody was raised against kLH-linked peptide corresponding to the C-terminus amino acids 1285 to 1308 of human erbB4/HER4.
C-Terminus
Recognizes human erbB4/HER4, Mr 185kD. Does not recognize erbB1 (EGFR), erbB2 or erbB3. Species cross-reactivity: Mouse and rat.
Western Blot Analysis: 1-4 ug/ml detects erbB4/HER4 in RIPA lysates from MCF-7 cells. Immunoprecipitation: 4 ug immunoprecipitates erbB4/HER4 from 500 ug of MCF-7 RIPA lysate. Immunoprecipitation/Western Blot Analysis: MCF-7 cell lysate was immunoprecipitated with 4 ug anti-erbB4/HER4. The immune complex was subsequently resolved by electrophoresis and transferred to nitrocellulose. Proteins were visualized using a secondary antibody conjugated to HRP and a chemiluminescence detection system.

Packaging

10 mM PBS, pH 7.4, 0.09% sodium azide
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
For research use only.

About ERBB4 / HER4

Q15303 NM_005235 NP_005226.1

ERBB4 Antibody, ERBB 4 Antibody, HER4 Antibody, p180 erb4 Antibody, p180erbB4 Antibody

Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins and EGF family members and regulates development of the heart, the central nervous system and the mammary gland, gene transcription, cell proliferation, differentiation, migration and apoptosis. Required for normal cardiac muscle differentiation during embryonic development, and for postnatal cardiomyocyte proliferation.

Requested From: United States
Date Requested: 9/24/2016

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