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Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.
Gene Name: | EPH receptor A6 |
Family/Subfamily: | Protein Kinase , Ephrin Receptor |
Synonyms: | EPHA6, Ephrin receptor EphA6, EPA6, EPH-like kinase 12, EHK2, Ek1, Ephrin type-A receptor 6, EHK-2, EK12, EPH homology kinase 2, EPH receptor A6, HEK12, PRO57066 |
Target Sequences: | AX250164 CAD38242.1 Q9UF33 |
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