Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone EN4] (IgG1) to Human Endothelium
IHC - Paraffin, IHC - Frozen, Flow Cytometry
Mouse Monoclonal [clone MRC OX-43] (IgG1) to Rat Endothelium
Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [MRC OX-43]
Protein G purified
Flow Cytometry (0.05 µg/10E6 cells)
Specificity and Use
Endothelium antibody was raised against rat peritoneal macrophages.
Anti-rat endothelium monoclonal antibody recognizes a surface protein of MW 90 kDa and generally reacts with all vascular endothelium in the rat except that of brain capillaries. This is the reciprocal tissue pattern to that of the transferrin receptor. I
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.