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Isoform 1 transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter.Isoform 2 may function in repression of RUNX1-mediated transactivation.
Gene Name: | E74-like factor 2 (ets domain transcription factor) |
Synonyms: | ELF2, E74-like factor 2, EU32, NERF-1A, New ETS-related factor, NERF, NERF-1B, NERF-1a,b, NERF-2 |
Target Sequences: | NM_006874 NP_006865.1 Q15723 |
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