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Interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex.
Gene Name: | EP300 interacting inhibitor of differentiation 2 |
Synonyms: | EID2, EID-2, CRI2, CREBBP/EP300 inhibitor 2 |
Target Sequences: | NP_940817.1 Q6X7S9 |
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