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Anti-EGLN3 / PHD3 Antibody (clone EG188e/d5, DY488) LS-C143246


Wt. Vol. Conc. Price
- 200 µl - $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Alternate Forms of this Antibody

LS-C143243 Unconjugated
LS-C143244 Biotin Conjugated
LS-C143245 DY650 Conjugated
LS-C143248 DY550 Conjugated

Most Popular EGLN3 / PHD3 Antibodies

Anti-EGLN3 / PHD3 Antibody (Internal) LS-C48987
Rabbit Polyclonal to Human EGLN3 / PHD3
Human, Rat
Western blot
Western blot Image
Anti-EGLN3 / PHD3 Antibody (aa108-119) LS-C54756
Goat Polyclonal to Human EGLN3 / PHD3
Human, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken
Western blot, ELISA
Western blot Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone EG188e/d5] (IgG1) to Human EGLN3 / PHD3
IHC - Paraffin, Western blot (applications tested for the base form of this product only)
DY488 Conjugated


Human EGLN3 / PHD3
Human (tested or 100% immunogen sequence identity)
Mouse, Rat, Bovine (at least 90% immunogen sequence identity)
IgG1 Monoclonal [EG188e/d5]
DyLight 488
Protein G purified


  • IHC - Paraffin
  • Western blot
  • (applications tested for the base form of this product only)

Specificity and Use

EGLN3 / PHD3 antibody was raised against partial recombinant human PHD3 protein (UniProt accession number Q9H6Z9). Percent identity by BLAST analysis: Bovine, Rat, Mouse (98%).
The applications listed have been tested for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.


50 mM sodium borate
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About EGLN3 / PHD3

Q9H6Z9 NM_022073 NP_071356.1

EGLN3 Antibody, HPH-1 Antibody, HIF prolyl hydroxylase 3 Antibody, HIF-prolyl hydroxylase 3 Antibody, HIFPH3 Antibody, PHD3 Antibody, EGL nine (C.elegans) homolog 3 Antibody, Egl nine homolog 3 Antibody, HIF-PH3 Antibody, HIFP4H3 Antibody

Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF2A. Hydroxylation on the NODD site by EGLN3 appears to require prior hydroxylation on the CODD site.


HIF Prolyl Hydroxylase 3 Antibody (EG188e/d5) - IHC of HIF Prolyl Hydroxylase 3 in human renal cancer using DAB with hematoxylin counterstain. This image was taken for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.

Western blot

Western blot
HIF Prolyl Hydroxylase 3 Antibody (EG188e/d5) - Western blot of HIF Prolyl Hydroxylase 3 in Lane 1: Cobalt chloride treated COS-7 nuclear extracts and Lane 2: Untreated COS-7 nuclear extracts. This image was taken for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.

Requested From: United States
Date Requested: 10/21/2016

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