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Human EGLN2 / PHD1 | |
Rabbit | |
Human, Mouse, Rat, Dog, Guinea pig (tested or 100% immunogen sequence identity) | |
Polyclonal | |
Unconjugated. Also available conjugated with Biotin, FITC, HRP. | |
Immunoaffinity purified | |
Unmodified |
EGLN2 / PHD1 antibody was raised against synthetic peptide from C-Terminus of human EGLN2 (Q96KS0, NP_444274). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Mouse, Rat, Guinea pig (100%); Monkey, Marmoset, Elephant (85%); Dog (84%). | ||
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C-Terminus | ||
Human EGLN2 / PHD1 | ||
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody. |
Lyophilized from PBS with 2% sucrose | |
Distilled water | |
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles. | |
For research use only. |
EGLN2 Antibody, EIT6 Antibody, EGL nine (C.elegans) homolog 2 Antibody, Egl nine homolog 2 Antibody, HPH-1 Antibody, HPH-3 Antibody, Estrogen-induced tag 6 Antibody, PHD1 Antibody, HIF-PH1 Antibody, HIF-prolyl hydroxylase 1 Antibody, HIFPH1 Antibody
Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF2A.
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