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Anti-DYRK2 Antibody (aa105-135) LS-C99892

Catalog Size Price
LS-C99892-400 400 µl Unavailable

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Anti-DYRK2 Antibody (aa105-135) LS-C99892
Rabbit Polyclonal to Human DYRK2
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IHC - Paraffin, Western blot
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Anti-DYRK2 Antibody (C-Terminus) IHC-plus™ LS-B7095
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Anti-DYRK2 Antibody (aa520-549) LS-C329485
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Anti-DYRK2 Antibody (aa434-483) IHC-plus™ LS-B11488
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Anti-DYRK2 Antibody LS-C412663
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100% Guaranteed Publications (1)
Rabbit Polyclonal to Human DYRK2
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human DYRK2
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Ammonium sulfate precipitation
Unmodified

Applications

  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)

Specificity and Use

LS-E9031 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C99892. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa105-135
This DYRK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 105-135 amino acids from the N-terminal region of human DYRK2.

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

Publications (1)

1
Mutual regulation between SIAH2 and DYRK2 controls hypoxic and genotoxic signaling pathways. Prez M, Garca-Limones C, Zapico I, Marina A, Schmitz ML, Muoz E, Calzado MA. Journal of molecular cell biology. 2012 4:316-30. [PubMed:22878263]

About DYRK2

Q92630 NM_006482 NP_006473.2

DYRK2 Antibody

Serine/threonine-protein kinase involved in the regulation of the mitotic cell cycle, cell proliferation, apoptosis, organization of the cytoskeleton and neurite outgrowth. Functions in part via its role in ubiquitin-dependent proteasomal protein degradation. Functions downstream of ATM and phosphorylates p53/TP53 at 'Ser-46', and thereby contributes to the induction of apoptosis in response to DNA damage.

Immunohistochemistry

Immunohistochemistry
DYRK2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human testis tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

Western blot
Western blot of lysate from 293 cell line, using DYRK2 Antibody (P46). Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.

Western blot

Western blot
The anti-DYRK2 antibody is used in Western blot to detect DYRK2 in 293 cell lysate.

Western blot

Western blot
Western blot of lysates from CEM, HeLa cell line (from left to right), using DYRK2 Antibody (P46). Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

Requested From: 
Date Requested: 10/24/2017

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