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DSG3 / Desmoglein 3
desmoglein 3
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
| Gene Name: | desmoglein 3 |
| Family/Subfamily: | Cadherin , not assigned-Cadherin |
| Synonyms: | DSG3, Balding, BAL, Cadherin family member 6, CDHF6, Desmoglein 3, Pemphigus vulgaris antigen, Desmoglein-3, PVA |
| Target Sequences: | NM_001944 NP_001935.2 P32926 |
Publications (9)
1
Development of chimeric molecules for recognition and targeting of antigen-specific B cells in pemphigus vulgaris. Proby CM, Ota T, Suzuki H, Koyasu S, Gamou S, Shimizu N, Wahl JK, Wheelock MJ, Nishikawa T, Amagai M. The British journal of dermatology. 2000 142:321-30. (WB)
[PubMed:10730768]
2
Protection against pemphigus foliaceus by desmoglein 3 in neonates. Wu H, Wang ZH, Yan A, Lyle S, Fakharzadeh S, Wahl JK, Wheelock MJ, Ishikawa H, Uitto J, Amagai M, Stanley JR. The New England journal of medicine. 2000 343:31-5. (ICC)
[PubMed:10882766]
3
The fate of desmosomal proteins in apoptotic cells. Weiske J, Schneberg T, Schrder W, Hatzfeld M, Tauber R, Huber O. The Journal of biological chemistry. 2001 276:41175-81. (ICC, WB, IP)
[PubMed:11500511]
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(4)
DSG3 / Desmoglein 3 Mouse anti-Human Monoclonal (6G2C11) Antibody
Human
ELISA, Flo, IHC-P, WB
Unconjugated
0.05 mg/$460
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
E. coli
6His, N-terminus
67.0 kDa
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$764
E. coli
His-SUMO
78.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
DSG3 / Desmoglein 3 Rabbit anti-Human Polyclonal (aa70-615) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
DSG3 / Desmoglein 3 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
DSG3 / Desmoglein 3 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
DSG3 / Desmoglein 3 Mouse anti-Human Monoclonal (5H10) Antibody
Human
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
0.1 ml/$386
DSG3 / Desmoglein 3 Mouse anti-Human Monoclonal (Biotin) (5H10) Antibody
Human
ICC, IF, IHC, IHC-P, IP, WB
Biotin Conjugated
0.1 ml/$416
DSG3 / Desmoglein 3 Mouse anti-Human Monoclonal (DY650) (5H10) Antibody
Human
ICC, IF, IHC, IHC-P, IP, WB
DY650 Conjugated
0.1 ml/$416
DSG3 / Desmoglein 3 Mouse anti-Human Monoclonal (DY488) (5H10) Antibody
Human
ICC, IF, IHC, IHC-P, IP, WB
DY488 Conjugated
0.1 ml/$416
DSG3 / Desmoglein 3 Mouse anti-Human Monoclonal (DY550) (5H10) Antibody
Human
ICC, IF, IHC, IHC-P, IP, WB
DY550 Conjugated
0.1 ml/$416
DSG3 / Desmoglein 3 Rabbit anti-Human Polyclonal (aa858-999) Antibody
Pig, Human
WB
Unconjugated
100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141
DSG3 / Desmoglein 3 Rabbit anti-Human Polyclonal (aa858-999) (APC) Antibody
Pig, Human
WB
APC Conjugated
100 µl/$387; 200 µl/$463; 500 µl/$778; 1 ml/$933; 2 ml/$1,194; 5 ml/$2,213
Yeast
6His, N-terminus
100 µg/$570; 20 µg/$395; 1 mg/$1,973
DSG3 / Desmoglein 3 Rabbit anti-Human Polyclonal (aa8-36) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
DSG3 / Desmoglein 3 Rabbit anti-Human Monoclonal (EP306) Antibody
Human
IHC-Fr, IHC-P
Unconjugated
0.1 ml/$409; 0.5 ml/$615; 1 ml/$1,004
DSG3 / Desmoglein 3 Rabbit anti-Human Monoclonal (Ready-to-Use) (EP306) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3 ml/$409; 7 ml/$509; 15 ml/$766
DSG3 / Desmoglein 3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
DSG3 / Desmoglein 3 Rabbit anti-Human Polyclonal (aa8-36) Antibody
Human
WB
Unconjugated
400 µl/$393
DSG3 / Desmoglein 3 Mouse anti-Human Monoclonal (Concentrated) (5G11) Antibody
Human
IF, IHC, IHC-P, IP, WB
Unconjugated, Concentrated
1 ml/$638
DSG3 / Desmoglein 3 Rabbit anti-Human Polyclonal (aa854-903) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
DSG3 / Desmoglein 3 Mouse anti-Human Monoclonal (5H10) Antibody
Human
Flo, IF, IP, WB
Unconjugated
20 µg/$371; 100 µg/$574
DSG3 / Desmoglein 3 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (5H10) Antibody
Human
Flo, IF, IP, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
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