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Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.
Gene Name: | DOT1-like histone H3K79 methyltransferase |
Synonyms: | DOT1L, DOT1, DOT1-like protein, KMT4, Lysine N-methyltransferase 4, KIAA1814, H3-K79-HMTase |
Target Sequences: | AK055359 NP_115871.1 Q8TEK3 |
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