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Anti-DOK1 Antibody (phospho-Tyr398) LS-C117333

Note: This antibody replaces LS-C64940, LS-C51517, LS-C34215

Ordering

Wt. Vol. Conc. Price
- 20 µl - $205
- 50 µl - $255
- 100 µl - $315
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular DOK1 Antibodies

Anti-DOK1 Antibody (C-Terminus) IHC-plus™ LS-B561
Rabbit Polyclonal to Human DOK1
Human
IHC - Paraffin, ICC, Western blot
Unconjugated
Immunohistochemistry Image
Anti-DOK1 Antibody (N-Terminus) LS-C50501
Rabbit Polyclonal to Human DOK1
Human
IHC
Unconjugated
Immunohistochemistry Image
Anti-DOK1 Antibody (N-Terminus, AP) LS-C218943
Rabbit Polyclonal (IgG) to Human DOK1
Human
IHC, Western blot, ELISA
AP Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human DOK1
Human, Mouse, Rat
Western blot, ELISA
Unconjugated

Details

Human DOK1
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot
  • ELISA

Specificity and Use

DOK1 antibody was raised against synthetic peptide from human p62 Dok around the phosphorylation site of Tyr398.
pTyr398
p62 Dok (Phospho-Tyr398) Antibody detects endogenous levels of p62 Dok only when phosphorylated at tyrosine398.

Packaging

PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Store at -20°C for up to one year.
For research use only.

About DOK1

Q99704 NM_001381 NP_001372.1

DOK1 Antibody, Docking protein 1 Antibody, Gap binding protein p62dok Antibody, p62(dok) Antibody, p62DOK Antibody, Pp62 Antibody

DOK1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.

Western blot

Western blot
Western blot of extracts from K562 cells treated with Starvation 24h, using p62 Dok (Phospho-Tyr398) Antibody. The lane on the right is treated with the synthesized peptide.
 

Requested From: United States
Date Requested: 12/3/2016

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