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Anti-DNTT / TdT Antibody (N-Terminus, clone HTdt-1/HTdt-2/ HTdt-3, FITC) LS-C58756

Ordering

Wt. Vol. Conc. Price
25 µg - - $745
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular DNTT / TdT Antibodies

Anti-DNTT / TdT Antibody LS-C18063
Rabbit Polyclonal (IgG) to Bovine DNTT / TdT
Bovine
IHC - Paraffin, IHC - Frozen
Unconjugated
Anti-DNTT / TdT Antibody (C-Terminus) IHC-plus™ LS-B9391
Rabbit Polyclonal (IgG) to Human DNTT / TdT
Human, Mouse, Rat
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-DNTT / TdT Antibody (Internal) LS-C210296
Rabbit Polyclonal (IgG) to Human DNTT / TdT
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone HTdt-1/HTdt-2/ HTdt-3] to Human DNTT / TdT
Human
Flow Cytometry
FITC Conjugated

Details

Human DNTT / TdT
Mouse
Human (tested or 100% immunogen sequence identity)
Monoclonal [HTdt-1/HTdt-2/ HTdt-3]
Fluorescein
Purified
Unmodified

Applications

Flow Cytometry (1:1)

Specificity and Use

N-Terminus
Is a mixture of 3 monoclonal antibodies specific for human terminal deoxynucleotidyl transferase (TdT). TdT is a DNA polymerase responsible for the catalysis of non-reversible addition of deoxynucleotides to the 3 end hydroxy groups of DNA. TdT levels are enhanced in all forms of acute lymphoblastic leukaemia (ALL) and in a significant number of chronic lymphoblastic leukaemia cases (CML). TdT is not expressed in the majority of myeloid leukemias, non-Hodgkins lymphomas or mature lymphoid leukemias.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. Membrane permeabilization is required for this application. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, 0.09% sodium azide, 1% BSA.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About DNTT / TdT

P04053 NM_004088 NP_004079.3

DNTT Antibody, DNA nucleotidylexotransferase Antibody, TDT Antibody, Terminal addition enzyme Antibody, Terminal transferase Antibody

DNTT / TdT is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers.

Requested From: United States
Date Requested: 12/6/2016

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