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Anti-DNMT3A Antibody (aa457-486) LS-C167495

Ordering

Wt. Vol. Conc. Price
- 400 µl - Unavailable

Most Popular DNMT3A Antibodies

Anti-DNMT3A Antibody (C-Terminus, clone 64B1446) LS-C522
Mouse Monoclonal [clone 64B1446] (IgG1) to Mouse DNMT3A
Mouse, Human
IHC, ICC, Western blot, Chromatin Immunoprecipitation
Unconjugated
Immunocytochemistry Image
Anti-DNMT3A Antibody (aa457-486) LS-C96546
Rabbit Polyclonal to Human DNMT3A
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-DNMT3A Antibody (clone 64B814.1, Biotin) LS-C148122
Mouse Monoclonal [clone 64B814.1] (IgG1) to Mouse DNMT3A
Mouse, Human
IHC - Frozen, Western blot
Biotin Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human DNMT3A
Human
Western blot
Unconjugated

Details

Human DNMT3A
Rabbit
Human (tested or 100% immunogen sequence identity)
Mouse, Rat, Chicken (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Protein A purified
Unmodified

Applications

Western blot (1:1000)

Specificity and Use

LS-E3779 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C167495. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa457-486
This Dnmt3a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 457-486 amino acids from the Central region of human Dnmt3a.

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About DNMT3A

Q9Y6K1 NM_022552 NP_072046.2

DNMT3A Antibody, DNA MTase HsaIIIA Antibody, DNMT3A2 Antibody, DNA methyltransferase HsaIIIA Antibody, M.HsaIIIA Antibody

Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells.

Western blot

Western blot
DNMT3A Antibody (CenterR478) western blot of HL-60 cell line lysates (35 ug/lane). The DNMT3A antibody detected the DNMT3A protein (arrow).
 

Requested From: 
Date Requested: 3/24/2017

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