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Anti-DNAM-1 / CD226 Antibody (RPE) LS-C44513

Note: This antibody replaces LS-C57785
Catalog Size Price
LS-C44513-100 100 tst Unavailable

Related Products

68 DNAM-1 / CD226 Antibodies

Most Popular DNAM-1 / CD226 Antibodies

Anti-DNAM-1 / CD226 Antibody (clone DX11, Low Endotoxin) LS-C44510
Mouse Monoclonal [clone DX11] (IgG1) to Human DNAM-1 / CD226
Human
Immunoprecipitation, Flow Cytometry, Functional Assay
Unconjugated, Low Endotoxin
Anti-DNAM-1 / CD226 Antibody (clone DX11, Azide-free) LS-C128017
Mouse Monoclonal [clone DX11] (IgG1) to Human DNAM-1 / CD226
Human
Immunoprecipitation, Flow Cytometry, Functional Assay
Unconjugated, Azide-free
Anti-DNAM-1 / CD226 Antibody (clone DX11, Biotin) LS-C204166
Mouse Monoclonal [clone DX11] (IgG1) to Human DNAM-1 / CD226
Human
Immunoprecipitation, Flow Cytometry
Biotin Conjugated
Anti-DNAM-1 / CD226 Antibody (aa307-335, Biotin) LS-C213165
Rabbit Polyclonal (IgG) to Human DNAM-1 / CD226
Human
Western blot, ELISA
Biotin Conjugated
Anti-DNAM-1 / CD226 Antibody (aa307-335, Azide-free, HRP) LS-C213167
Rabbit Polyclonal (IgG) to Human DNAM-1 / CD226
Human
Western blot, ELISA
HRP Conjugated, Azide-free

100% Guaranteed
Mouse Monoclonal (IgG1) to Human DNAM-1 / CD226
Human
Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
RPE Conjugated

Details

Human DNAM-1 / CD226
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
R. Phycoerythrin. Also available Unconjugated or conjugated with Biotin, FITC.
Protein G purified
Unmodified

Applications

  • Immunoprecipitation
  • Flow Cytometry (1:1)
  • (applications tested for the base form of this product only)

Specificity and Use

DNAM-1 / CD226 antibody was raised against human cytotoxic T lymphocyte clone.
Recognizes human CD226, a 65kD glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes. Clone DX11 is reported to inhibit T- and NK cell mediated cytotoxicity against tumor cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells. XXX recommend the use of MCA2257XZ for functional studies.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 1 x 10^6 cells in 100 ul. Method sheets are available on request.

Packaging

Lyophilized, PBS, pH 7.4, 0.09% sodium azide, 1.0% BSA.
100 tst Distilled Water.
For research use only.

About DNAM-1 / CD226

Q15762 NM_006566 NP_006557.2

CD226 Antibody, Adhesion glycoprotein Antibody, CD226 molecule Antibody, CD226 antigen Antibody, DNAM-1 Antibody, DNAM1 Antibody, DNAX accessory molecule-1 Antibody, TLiSA1 Antibody, PTA1 Antibody, DNAX accessory molecule 1 Antibody

DNAM-1 / CD226 is a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

Requested From: 
Date Requested: 8/23/2017

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