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Anti-DNAM-1 / CD226 Antibody (Biotin) LS-C9112

Catalog Size Price
LS-C9112-100 100 µg (0.1 mg/ml) Unavailable

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78 DNAM-1 / CD226 Antibodies

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Anti-DNAM-1 / CD226 Antibody (Biotin) LS-C9112
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Anti-DNAM-1 / CD226 Antibody (clone DX11, Low Endotoxin) LS-C44510
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Anti-DNAM-1 / CD226 Antibody (clone DX11, Biotin) LS-C204166
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Anti-DNAM-1 / CD226 Antibody (aa307-335, Biotin) LS-C213165
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Anti-DNAM-1 / CD226 Antibody (aa307-335, Azide-free, HRP) LS-C213167
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100% Guaranteed
Mouse Monoclonal (IgG1) to Human DNAM-1 / CD226
Human
Immunoprecipitation, Flow Cytometry
Biotin Conjugated

Details

Human DNAM-1 / CD226
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Biotin
Protein G purified
Unmodified

Applications

  • Immunoprecipitation
  • Flow Cytometry

Specificity and Use

DNAM-1 / CD226 antibody was raised against human cytotoxic T lymphocyte clone.
Recognizes human CD226. Reported to inhibit T- and NK cell mediated cytotoxicity against tumor cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.
Suitable for use in Flow Cytometry and Immunoprecipitation. Flow Cytometry: Neat 1:10. Use 10 ul of the suggested working dilution to label 1x1E6 cells in 100ul. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, pH 7.4, 1.0% BSA, 0.09% sodium azide.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About DNAM-1 / CD226

Q15762 NM_006566 NP_006557.2

CD226 Antibody, Adhesion glycoprotein Antibody, CD226 molecule Antibody, CD226 antigen Antibody, DNAM-1 Antibody, DNAM1 Antibody, DNAX accessory molecule-1 Antibody, TLiSA1 Antibody, PTA1 Antibody, DNAX accessory molecule 1 Antibody

DNAM-1 / CD226 is a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

Requested From: 
Date Requested: 5/22/2018

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