Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma-mediated transcriptional activity. Isoform 2 may play a role in neuromuscular junction development as an effector of the MUSK signaling pathway.
Gene Name: | DnaJ (Hsp40) homolog, subfamily A, member 3 |
Synonyms: | DNAJA3, DnaJ protein Tid-1, HTID-1, HCA57, TID1 |
Target Sequences: | NM_005147 NP_005138.3 Q96EY1 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.