Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Delipidated and defibrinated
Specificity and Use
DNA ss antibody was raised against derived from donor human serum.
Displays only Anti-ssDNA activity when tested by ELISA. Undiluted antibody shows a strong Scl-70 precipitin band. Specificity verified by a precipitin line of identity with the CDC-AF reference serum and by ELISA procedures using both native DNA and ssDNA. Does not cross-react at a dilution of 1:100 when tested against purified Ro/SS-A, La/SS-B, Sm, Scl-70, nRNP, dsDNA, or Jo-1 antigens in an ELISA system designed to detect IgG antibody.