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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DKK2 Antibody (Asn70) LS‑C64748
Antibody
DKK2 antibody LS-C64748 is an unconjugated rabbit polyclonal antibody to human DKK2. Validated for WB.
Catalog
Size
Price
LS-C64748-100
100 µl
Unavailable

Popular DKK2 Products

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Anti-DKK2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8226 dilution 2.5-5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse, Human, Monkey, Rat, Bat, Dog, Guinea pig, Horse, Pig, Rabbit
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot

Product Description

DKK2 antibody LS-C64748 is an unconjugated rabbit polyclonal antibody to human DKK2. Validated for WB.
About DKK2
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Q9UBU2 NM_014421 NP_055236.1

DKK2 Antibody, DKK-2 Antibody, Dickkopf homolog 2 Antibody, Dickkopf related protein-2 Antibody, HDkk-2 Antibody, Dickkopf-2 Antibody, Dickkopf-related protein 2 Antibody


Specifications

Target
Human DKK2
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Immunogen
DKK2 antibody was raised against synthetic peptide (KLHcoupled) corresponding to residues surrounding Asn70 of human DKK2.
Epitope
Asn70
Specificity
Detects transfected levels of human DKK2 protein. This antibody does not cross-react with DKK1.
Usage
Suitable for use in Western Blot. Western Blot: 1:1000.
Presentation
10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 100 ug/ml BSA, 50% glycerol.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/22/2018

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