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Anti-DHX58 / LGP2 Antibody (C-Terminus) LS-C53209

Note: This antibody replaces LS-C130452
Catalog Size Price
LS-C53209-50 50 µg (1 mg/ml) Unavailable

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100% Guaranteed
Rabbit Polyclonal (IgG) to Human DHX58 / LGP2
Human, Mouse, Rat
Western blot, ELISA


Human DHX58 / LGP2
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


  • Western blot (1 - 2 µg/ml)

  • IHC - Paraffin

Specificity and Use

LS-E30398 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-C53209. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
At least four isoforms of LGP2 are known to exist.


PBS, 0.02% sodium azide.
Store at 4°C for 3 months and -20°C, stable for up to 1 year. Avoid repeated freeze-thaw cycles.
For research use only.

About DHX58 / LGP2

Q96C10 NM_024119 NP_077024.2

DHX58 Antibody, D11LGP2 Antibody, D11lgp2e Antibody, Protein D11Lgp2 homolog Antibody, LGP2 Antibody, RIG-I-like receptor 3 Antibody, RNA helicase LGP2 Antibody, RLR Antibody, Ortholog of mouse D11lgp2 Antibody, RIG-I-like receptor LGP2 Antibody, RLR-3 Antibody

Acts as a regulator of DDX58/RIG-I and IFIH1/MDA5 mediated antiviral signaling. Cannot initiate antiviral signaling as it lacks the CARD domain required for activating MAVS/IPS1-dependent signaling events. Can have both negative and positive regulatory functions related to DDX58/RIG-I and IFIH1/MDA5 signaling and this role in regulating signaling may be complex and could probably depend on characteristics of the infecting virus or target cells, or both.

Western blot

Western blot analysis of LGP2 in rat kidney tissue lysate with LGP2 antibody at (A) 1 and (B) 2 µg/mL.
Western blot analysis of LGP2 in rat kidney tissue lysate with LGP2 antibody at (A) 1 and (B) 2 µg/mL.

Western blot

Western blot of LGP2 in rat kidney tissue lysate with LGP2 antibody at (A) 1 and (B) 2 ug/ml.
Western blot of LGP2 in rat kidney tissue lysate with LGP2 antibody at (A) 1 and (B) 2 ug/ml.

Requested From: 
Date Requested: 5/20/2018

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