Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone Dengue 1-11(3)] (IgG2a) to Dengue Virus
IHC - Paraffin, Western blot, ELISA
Dengue Virus (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [Dengue 1-11(3)]
IHC - Paraffin
Specificity and Use
Recognizes all four dengue virus serotypes (DEN-1, DEN-2, DEN-3 and DEN-4) of the genus Flavivirus. The dengue virus is responsible for the tropical and sub-tropical diseases, dengue (DF) and dengue hemorrhagic fever (DHF), transmitted to individuals through the bite of the Aedes mosquito. The global distribution of dengue is expanding and comparable to that of malaria, with symptoms ranging from a mild viral syndrome of high fever, rash, headache, fatigue and muscle and joint pain, to the more severe and sometimes fatal DHF. Each dengue virus serotype is antigenically distinct, such that infection only provides an individual with immunity to the causative serotype, with the possibility of further infection by a different serotype or even multiple serotypes. Detects an anti-E/envelope specific band of 61kD under reducing conditions in Western blotting. A weak secondary band of 80kD may also be apparent.
Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH6.0 is recommended for this purpose.
PBS, 0.05% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.