Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
IHC - Frozen
Specificity and Use
Recognizes an epitope within the class II MHC complex. In normal tissue identifies dendritic cells and a proportion of B lymphocytes. Within the macrophage/dendritic cell populations the epitope seen by 3H2075 is co-expressed with RFD7 by a subset of cells that exhibit suppressive activity on T cell stimulation. It will not bind to monocytes or any cells within the granulocyte series.