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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DEC‑205 / CD205 / LY75 Antibody (Extracellular Domain, APC) LS‑C130553
Antibody
LY75 antibody LS-C130553 is an APC-conjugated rat monoclonal antibody to mouse LY75 (DEC-205 / CD205). Validated for Flow.
Catalog
Size
Price
LS-C130553-100
100 tst
Unavailable

Popular DEC-205 / CD205 / LY75 Products

Anti-LY75 / DEC-205 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2669 concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin
Antibody
Species: Mouse
Applications: IHC, IHC - Frozen
Antibody
Species: Mouse
Applications: IHC, IHC - Frozen, Flow Cytometry
Formalin-fixed and paraffin-embedded human spleen tissue reacted with LY75 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry
Antibody
Species: Bovine, Sheep
Applications: IHC, IHC - Frozen, Immunoprecipitation, Flow Cytometry

Product Description

LY75 antibody LS-C130553 is an APC-conjugated rat monoclonal antibody to mouse LY75 (DEC-205 / CD205). Validated for Flow.
About DEC-205 / CD205 / LY75
LY75/CD205/DEC-205 is an integral membrane protein homologous to the macrophage mannose receptor and functions as an antigen-uptake receptor on dendritic cells. DEC-205 is rapidly taken up by means of coated pits and vesicles and is delivered to a multivesicular endosomal compartment that resembles the MHC class II-containing vesicles. O60449 NM_002349 NP_002340.2

LY75 Antibody, CD205 Antibody, CLEC13B Antibody, CD205 antigen Antibody, LY-75 Antibody, Lymphocyte antigen 75 Antibody, DEC-205 Antibody, gp200-MR6 Antibody


Specifications

Target
Mouse DEC-205 / CD205 / LY75
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal
Conjugations
Allophycocyanin
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Flow Cytometry
Immunogen
Purified, E. coli-derived, recombinant mouse Ly-75 (aa216-503) extracellular domain.
Epitope
Extracellular Domain
Specificity
Recognizes mouse Ly-75.
Usage
Suitable for use in Flow Cytometry. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
Sodium chloride, 0.5% BSA, 0.1% sodium azide
Storage
May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 1 year. Freezing Allophycocyanin conjugates will result in a substantial loss of enzymatic activity.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/18/2018

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