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DDH / AKR1C1

aldo-keto reductase family 1, member C1

DDH / AKR1C1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Gene Name: aldo-keto reductase family 1, member C1
Synonyms: AKR1C1, 2-ALPHA-HSD, 20-alpha-HSD, Aldo-keto reductase C, Bile acid binding protein, Chlordecone reductase homolog, DDH1, Dihydrodiol dehydrogenase 2, DD1, DDH, Dihydrodiol dehydrogenase 1/2, DD1/DD2, Dihydrodiol dehydrogenase 1, H-37, HAKRC, HBAB, Indanol dehydrogenase, MBAB
Target Sequences: NM_001353 NP_001344.2 Q04828

Publications (2)

1
Expression of aldo-keto reductase 1C23 in the equine corpus luteum in different luteal phases. Kozai K, Hojo T, Tokuyama S, Szóstek AZ, Takahashi M, Sakatani M, Nambo Y, Skarzynski DJ, Okuda K. The Journal of reproduction and development. 2014 60:150-4. (WB; Human) [PubMed:24492656] [PMC:PMC3999394] Related Antibodies: LS-B6269.
2
Androgen deficiency during mid- and late pregnancy alters progesterone production and metabolism in the porcine corpus luteum. Grzesiak M, Knapczyk-Stwora K, Ciereszko RE, Golas A, Wieciech I, Slomczynska M. Reproductive sciences (Thousand Oaks, Calif.). 2014 Jun;21:778-90. (WB; Human) [Full Text Article] [PubMed:24429677] [PMC:PMC4016731] Related Antibodies: LS-B12017.

☰ Filters
Antibodies (31)
Proteins (5)
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Primary (31)
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DDH / AKR1C1 (39)
Human (34)
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DDH / AKR1C1 Antibody - Anti-AKR1C1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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DDH / AKR1C1 Mouse anti-Human Monoclonal (AT6D10) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
DDH / AKR1C1 Antibody - Anti-DDH / AKR1C1 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 7.5 ug/ml.
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DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa22-248) Antibody
Mouse, Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µl/$460
DDH / AKR1C1 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa50-99) Antibody
Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$485
DDH / AKR1C1 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa50-99) (HRP) Antibody
Human, Monkey, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
DDH / AKR1C1 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa50-99) (Biotin) Antibody
Human, Monkey, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
DDH / AKR1C1 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa50-99) (FITC) Antibody
Human, Monkey, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
DDH / AKR1C1 Antibody - Immunohistochemical analysis of AKR1C1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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DDH / AKR1C1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
DDH / AKR1C1 Antibody - AKR1C1 monoclonal antibody (M01), clone 1B3. Western Blot analysis of AKR1C1 expression in HeLa.
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DDH / AKR1C1 Mouse anti-Human Monoclonal (1B3) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
DDH / AKR1C1 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa99-148) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
DDH / AKR1C1 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa99-148) (HRP) Antibody
Human, Chimpanzee, Orangutan
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
DDH / AKR1C1 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa99-148) (Biotin) Antibody
Human, Chimpanzee, Orangutan
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
DDH / AKR1C1 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa99-148) (FITC) Antibody
Human, Chimpanzee, Orangutan
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
DDH / AKR1C1 Antibody - Immunohistochemistry of paraffin-embedded Human colon cancer using AKR1C1 Polyclonal Antibody at dilution of 1:30.
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DDH / AKR1C1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
DDH / AKR1C1 Antibody
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DDH / AKR1C1 Rabbit anti-Human Polyclonal (aa2-218) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
DDH / AKR1C1 Antibody - 1:100 staining human uterus tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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DDH / AKR1C1 Rabbit anti-Human Polyclonal Antibody
Human, Monkey
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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DDH / AKR1C1 Rabbit anti-Human Polyclonal (30-110 aa, N-terminal) Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
DDH / AKR1C1 Antibody - Immunofluorescence staining of HepG2 cells at a dilution of 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 °C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L) .
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DDH / AKR1C1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$294; 100 µg/$360
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DDH / AKR1C1 Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
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DDH / AKR1C1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
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DDH / AKR1C1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
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DDH / AKR1C1 Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
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DDH / AKR1C1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
DDH / AKR1C1 Antibody - Western blot of AKR1C1 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate.
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DDH / AKR1C1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
DDH / AKR1C1 Antibody - Western blot analysis of extracts of various cell lines, using AKR1C1 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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DDH / AKR1C1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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DDH / AKR1C1 Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-25 of 39 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).