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DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity.Survival-promoting peptide promotes survival of neurons and displays phosphatase activity. It may bind IgG.
Gene Name: | dermcidin |
Synonyms: | DCD, AIDD, Dermcidin, DSEP, DCD-1, HCAP, PIF, Preproteolysin, Proteolysis inducing factor, Survival promoting peptide |
Target Sequences: | P81605 P81605 |
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