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DBN1 / Drebrin is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.
Gene Name: | drebrin 1 |
Synonyms: | DBN1, D0S117E, Drebrin-1, Drebrin, Drebrin E, Drebrin 1, Drebrin E2 |
Target Sequences: | NM_004395 NP_004386.2 Q16643 |
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