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Anti-DACH2 Antibody (aa145-173) LS-C167261

Ordering

Wt. Vol. Conc. Price
- 400 µl - Unavailable

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23 DACH2 Antibodies

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Anti-DACH2 Antibody (aa145-173) LS-C167261
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Rabbit Polyclonal to Human DACH2
Human
Western blot
Unconjugated

Details

Human DACH2
Rabbit
Human (tested or 100% immunogen sequence identity)
Mouse (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Protein A purified
Unmodified

Applications

Western blot (1:1000)

Specificity and Use

LS-E2299 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C167261. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa145-173
This DACH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-173 amino acids from the N-terminal region of human DACH2.

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About DACH2

Q96NX9 NM_053281 NP_444511.1

DACH2 Antibody, Dachshund homolog 2 Antibody

Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator for SIX1 and SIX6. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. Is recruited with SIX6 to the p27Kip1 promoter in embryonal retina. SIX6 corepression seems also to involve NCOR1, TBL1, HDAC1 and HDAC3. May be involved together with PAX3, SIX1, and EYA2 in regulation of myogenesis.

Western blot

Western blot
DACH2 Antibody western blot of HepG2,Jurkat cell line lysates (35 ug/lane). The DACH2 antibody detected the DACH2 protein (arrow).

Requested From: 
Date Requested: 4/24/2017

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