Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
Cytokeratin 5+6 antibody was raised against purified Cytokeratin 5 and 6.
Stains basal cells and part of the stratum spinosum in normal squamous epithelium and part of the basal layer of prostate gland epithelium. It does not stain other normal simple layer glandular epithelium.
Suitable for use in Immunohistochemistry. Immunohistochemistry: 1:50-1:200. Formalin- fixed, paraffin-embedded tumor tissue studies, and may be used to distinguish squamous carcinoma from adenoma. Requires high temperature antigen retrieval using 0.01 M EDTA solution; boil for 15 minutes, then cool down for at least 15-20 minutes at room temperature. Positive control: Skin.