Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human CYP3A4 / Cytochrome P450 3A4
IHC, Western blot
Human CYP3A4 / Cytochrome P450 3A4
Human (tested or 100% immunogen sequence identity)
Specificity and Use
CYP3A4 / Cytochrome P450 3A4 antibody was raised against synthetic peptide from human Cytochrome P450 Enzyme CYP3A4.
Recognizes human cytochrome P450 enzyme CYP3A4 in hepatic microsomal fraction. May show reactivity to CYP3A7 due to sequence homology. No cross-reactivity is observed with other cytochrome P450 enzymes.
Suitable for use in Western Blot and Immunohistochemistry. Immunohistochemistry: Formaldehyde-treated sections.
No preservative added.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
CYP3A4 / Cytochrome P450 3A4 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents.