The Immunohistochemistry Antibody Company
|Human (tested or 100% immunogen sequence identity)|
|CYP2A6 antibody was raised against synthetic peptide from C-Terminus of human CYP2A6 (P11509, NP_000753). Percent identity by BLAST analysis: Human, Gorilla (100%); Gibbon (92%); Monkey (85%).|
|Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.|
|Lyophilized from PBS with 2% sucrose|
|Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.|
|For research use only.|
CYP2A6 Antibody, CYP2A Antibody, Cytochrome P450(I) Antibody, CYPIIA6 Antibody, p450PB Antibody, p450C2A Antibody, Coumarin 7-hydroxylase Antibody, CYP2A3 Antibody, Cytochrome P450 2A6 Antibody, Cytochrome P450 IIA3 AntibodyThis gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals.