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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CRTC2 / TORC2 Antibody (aa541‑552) LS‑C139781
TORC2 antibody LS-C139781 is an unconjugated goat polyclonal antibody to TORC2 (CRTC2) from mouse, rat and hamster. Validated for Peptide-ELISA and WB.
Catalog
Size
Price
LS-C139781-100
100 µg
Unavailable

Popular CRTC2 / TORC2 Products

IHC of paraffin-embedded ovary tumor tissues (left) and lung cancer (right) using CRTC2 mouse monoclonal antibody with DAB staining.
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Applications: IHC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Anti-CRTC2 / TORC2 antibody IHC staining of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Rabbit
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Anti-CRTC2 / TORC2 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Detection of Human TORC2 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti- TORC2 used at a dilution of 1:1000 (1 Detection: DAB.
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Species: Human, Mouse
Applications: IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot

Product Description

TORC2 antibody LS-C139781 is an unconjugated goat polyclonal antibody to TORC2 (CRTC2) from mouse, rat and hamster. Validated for Peptide-ELISA and WB.
About CRTC2 / TORC2
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Q53ET0 NP_859066.1

CRTC2 Antibody, Transducer of CREB protein 2 Antibody, TORC-2 Antibody, TORC2 Antibody


Specifications

Target
Mouse CRTC2 / TORC2
Host
Goat
Reactivity
Mouse, Rat, Hamster (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (0.03 - 0.1 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:32000)
Immunogen
CRTC2 / TORC2 antibody was raised against synthetic peptide C-HGQQPYHRPIND from an internal region of mouse CRTC2 / TORC2 (NP_859066.1). Percent identity by BLAST analysis: Mouse, Rat, Hamster (100%).
Blocking Peptide
LS-E27679 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C139781. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa541-552
Specificity
Mouse CRTC2 / TORC2.
Usage
Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Approx 75kD band observed in Mouse and Rat Brain and Spinal Cord lysates (calculated MW of 73.3kD according to Mouse NP_859066.1 and 73.1kD according to Rat NP_001029067.1). Recommended concentration: 0.03-0.1 ug/ml.
Presentation
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

CRTC2 antibody (0.03 ug/ml) staining of Rat Spinal Cord lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
CRTC2 antibody (0.03 ug/ml) staining of Rat Spinal Cord lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

CRTC2 antibody (0.03 ug/ml) staining of Rat Spinal Cord lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
CRTC2 antibody (0.03 ug/ml) staining of Rat Spinal Cord lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

CRTC2 antibody (0.03 ug/ml) staining of Rat Spinal Cord lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
CRTC2 antibody (0.03 ug/ml) staining of Rat Spinal Cord lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

CRTC2 antibody (0.03 ug/ml) staining of Rat Spinal Cord lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
CRTC2 antibody (0.03 ug/ml) staining of Rat Spinal Cord lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


Requested From: 
Date Requested: 6/25/2018

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