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Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping.
Gene Name: | cleavage and polyadenylation specific factor 6, 68kDa |
Synonyms: | CPSF6, CPSF 68 kDa subunit, CFIM, HPBRII-4, HPBRII-7, Protein HPBRII-4/7, CFIM68 |
Target Sequences: | NM_007007 NP_008938.2 Q16630 |
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