Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Specificity and Use
Anti-Human Complement Component C3a polyclonal antibody reacts with human C3a. C3a is a 9 KDa, 77 amino acid peptide, and is one of the cleavage products formed when C3 convertase splits C3 into C3a and C3b. C3 along with C1, C2 and C4 is involved in the
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, 40% glycerol, EIA grade BSA.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.
About Complement C3a
C3a is one of the proteins formed by the cleavage of complement component 3; the other is C3b. C3a is a 77 residue peptide that binds to the C3a receptor (C3aR) a class A G protein-coupled receptor. It stimulates mast cell degranulation, thus triggering an immune response. C3a plays an important role in chemotaxis, though not as important a role as C5a. It is also an anaphylatoxin and the precursor of the important cytokine (adipokine) ASP through its interaction with carboxypeptidase B.