Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone GF1] (IgG1,k) to Human Complement C3a
Human Complement C3a
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [GF1]
Specificity and Use
Complement C3a antibody was raised against human C3a (1, 2).
Human C3a. Does not cross-react with C4a or C5a (2, 3).
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
0.01 M phosphate buffer, pH 7.4, 0.14 M sodium chloride, 15 mM sodium azide
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months.
For research use only.
About Complement C3a
C3a is one of the proteins formed by the cleavage of complement component 3; the other is C3b. C3a is a 77 residue peptide that binds to the C3a receptor (C3aR) a class A G protein-coupled receptor. It stimulates mast cell degranulation, thus triggering an immune response. C3a plays an important role in chemotaxis, though not as important a role as C5a. It is also an anaphylatoxin and the precursor of the important cytokine (adipokine) ASP through its interaction with carboxypeptidase B.