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Anti-Complement C3 Antibody LS-C44997


Wt. Vol. Conc. Price
100 µg - 1 mg/ml $525
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular Complement C3 Antibodies

Anti-Complement C3 Antibody (clone 11H9) LS-C22283
Rat Monoclonal [clone 11H9] (IgG2a) to Mouse Complement C3
IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry, ELISA
Anti-Complement C3 Antibody (clone 6C9, FITC) LS-C62855
Mouse Monoclonal [clone 6C9] (IgG1) to Human Complement C3
Human, Mouse
Flow Cytometry, ELISA
FITC Conjugated
Flow Cytometry Image
Anti-Complement C3 Antibody (clone 10C7, FITC) LS-C62858
Mouse Monoclonal [clone 10C7] (IgG1) to Human Complement C3
Flow Cytometry
FITC Conjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG1) to Human Complement C3
IHC - Frozen, Flow Cytometry, ELISA


Human Complement C3
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Protein A purified


  • IHC - Frozen
  • Flow Cytometry

Specificity and Use

Complement C3 antibody was raised against purified human C3d (neoantigen).
Specific for human complement component 3d (C3d) neoantigen, a 33kD polypeptide fragment generated over the course of complement activation in which where complement 3 (C3) convertases cleave C3 to C3b, which is further degraded into iC3b and C3dg/C3d. C3d is involved in the regulation of many aspects of the immune response, including antigen processing and presentation. The C3d/antigen complex mediates B cell activation by simultaneously binding antigen-specific surface bound immunoglobulin and CD21, lowering the complement activation threshold. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation.


Borate buffered saline, 0.1% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About Complement C3

P01024 NM_000064 NP_000055.2

C3 Antibody, AHUS5 Antibody, ARMD9 Antibody, Complement component C3 Antibody, CPAMD1 Antibody, Complement C3 Antibody, ASP Antibody, Complement component 3 Antibody

C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process.

Requested From: United States
Date Requested: 10/26/2016

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