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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CNR2 / CB2 Antibody (aa1‑33) IHC‑plus™ LS‑B2263
Note: This antibody replaces LS-C12385
CB2 antibody LS-B2263 is an unconjugated rabbit polyclonal antibody to CB2 (CNR2) from human and rat. Validated for Flow, ICC, IHC and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B2263-50
50 µl
Unavailable

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Product Description

CB2 antibody LS-B2263 is an unconjugated rabbit polyclonal antibody to CB2 (CNR2) from human and rat. Validated for Flow, ICC, IHC and WB. Tested on 20 paraffin-embedded human tissues.
About CNR2 / CB2
The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. P34972 NM_001841 NP_001832.1

CNR2 Antibody, Cannabinoid receptor 2 Antibody, CB2 Antibody, CB2 cannabinoid receptor Antibody, CX5 Antibody, CB2R Antibody, HCB2 Antibody, Cannabinoid CB2 receptor Antibody, CB-2 Antibody, CB2 receptor Antibody


Specifications

Target
Human CNR2 / CB2
Host
Rabbit
Reactivity
Human, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:100)
  • IHC - Frozen
  • ICC
  • Western blot
  • Flow Cytometry
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CNR2 / CB2 antibody was raised against recombinant human CB2 (cannabinoid receptor 2) fusion protein (aa 1-33).
Epitope
aa1-33
Specificity
Recognizes human CB2. Bands of ~60kD from human spinal cord homogenate and ~40kD from RBL2H3 cells representing different glycosylated forms of CB2 are detected by Western Blot.
Usage
Immunohistochemistry: LS-B2263 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2263 was determined to be 1:100.
Presentation
PBS, 50% glycerol, 1 mg/ml BSA, 0.05% sodium azide.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Immunohistochemistry

Anti-CNR2 / CB2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2263 dilution 1:100.
Anti-CNR2 / CB2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2263 dilution 1:100.

Immunohistochemistry

Anti-CNR2 / CB2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2263 dilution 1:100.
Anti-CNR2 / CB2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2263 dilution 1:100.

Immunohistochemistry

Anti-CNR2 / CB2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2263 dilution 1:100.
Anti-CNR2 / CB2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2263 dilution 1:100.

Immunohistochemistry

Anti-CNR2 / CB2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2263 dilution 1:100.
Anti-CNR2 / CB2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2263 dilution 1:100.


Requested From: 
Date Requested: 6/23/2018

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