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CLIP3 is a member of the cytoplasmic linker protein 170 family. Members of this protein family contain a cytoskeleton-associated protein glycine-rich domain and mediate the interaction of microtubules with cellular organelles. The encoded protein plays a role in T cell apoptosis by facilitating the association of tubulin and the lipid raft ganglioside GD3. The encoded protein also functions as a scaffold protein mediating membrane localization of phosphorylated protein kinase B. Alternatively spliced transcript variants have been observed for this gene.
Gene Name: | CAP-GLY domain containing linker protein 3 |
Synonyms: | CLIP3, CLIPR-59, CLIPR59, Restin-like 1, RSNL1 |
Target Sequences: | H20608 Q96DZ5 Q96DZ5 |
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