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Anti-CLDN4 / Claudin 4 Antibody (C-Terminus) IHC-plus™ LS-B2257

Note: This antibody replaces LS-C6153


Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular CLDN4 / Claudin 4 Antibodies

Anti-CLDN4 / Claudin 4 Antibody LS-C35944
Mouse Monoclonal (IgG2a) to Human CLDN4 / Claudin 4
Flow Cytometry, ELISA
Anti-CLDN4 / Claudin 4 Antibody (C-Terminus) IHC-plus™ LS-B2257
Mouse Monoclonal (IgG1) to Human CLDN4 / Claudin 4
Human, Rat, Dog
IHC - Paraffin, Immunofluorescence, Western blot
Immunohistochemistry Image

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Mouse Monoclonal (IgG1) to Human CLDN4 / Claudin 4
Human, Rat, Dog
IHC - Paraffin, Immunofluorescence, Western blot


Human CLDN4 / Claudin 4
Human, Rat, Dog (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Protein A purified


  • IHC - Paraffin (5 µg/ml)
  • Immunofluorescence (1 - 3 µg/ml)
  • Western blot (1 - 3 µg/ml)

Specificity and Use

CLDN4 / Claudin 4 antibody was raised against synthetic peptide corresponding to a 22 amino acid sequence derived from the C-terminal region of human Claudin 4.
Recognizes the human ~22kD Claudin 4 protein and does not cross-react with the protein at 55kD. Species cross-reactivity: rat ileum homogenates and canine MDCK cell lysates by Western Blot and Immunofluorescence. Reactivity has also been confirmed with formalin-fixed, paraffin-embedded (FFPE) human normal colon and colon cancer tissues by Immunohistochemistry.
Immunohistochemistry: LS-B2257 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2257 was determined to be 5 ug/ml.


PBS, pH 7.4, 0.1% sodium azide.
Short term +4°C (no longer than one week); Long term -20°C; Aliquot to avoid freeze/thaw cycles.
For research use only.

About CLDN4 / Claudin 4

O14493 NM_001305 NP_001296.1

CLDN4 Antibody, Claudin-4 Antibody, CPE-receptor Antibody, CPETR Antibody, CPETR1 Antibody, Claudin 4 Antibody, CPE-R Antibody, HCPE-R Antibody, WBSCR8 Antibody, CPER Antibody

The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life.


Anti-CLDN4 / Claudin 4 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2257 concentration 5 ug/ml.

Requested From: United States
Date Requested: 10/22/2016

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