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CLDN2 / Claudin 2 belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.
Gene Name: | claudin 2 |
Family/Subfamily: | Claudin , not assigned-Claudin |
Synonyms: | CLDN2, Claudin 2, SP82, Claudin-2 |
Target Sequences: | NM_020384 NP_065117.1 P57739 |
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